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Coherence imaging is the science (and sometimes art) of interfering two light beams to form an "image".
This has become increasingly useful for rendering 3D images in biological tissues, essentially an
extended depth microscopy.
What fascinates me is the idea of tailoring what that "image" consists of. Do you want to visualize
linear motion using Doppler imaging, Brownian motion via standard deviation imaging, or specific
scatterer sizes by looking at the angular scattering spectrum? What new metrics can we devise that will
allow us to see the most important biological processes?
I also like to think about ways that we can use nanoparticles as biological imaging probes, because
they can be manipulated and measured with optics, and coupled with biomolecules to promote
a specific reaction. The possibility of "in vivo non-invasive histology" using coherence imaging
is truly exciting, and may bridge research on the scales of the individual cell and the whole organism.
However, we must temper any nanotechnological research with caution, using
materials that are minimally toxic and have the best outlook for eventual human use.
I am currently in the process of building up my laboratory, which is located in room 157 Phillips Hall.
For an idea of what I've done in the past please visit my publications page, which may give you a taste of what to expect here in the future.
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